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1

Cytotoxicity of 5-nitro-2 1-deoxyuridine by in vivo inhibition of thymidylate synthetase

Wendy Washtien, Akira Matsuda, Yusuke Wataya, Daniel V. Santi

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 244 KB

english, 1978

2

Mechanism of carbinolamine formation

Sayer, J. M., Pinsky, B., Schonbrunn, A., Washtien, W.

Journal:

Journal of the American Chemical Society

Year:

1974

Language:

english

File:

PDF, 1.48 MB

english, 1974

3

Bifunctional Thymidylate Synthase-dihydrofolate Reductase from Leishmania tropica: Sequence Homology with the Corresponding Monofunctional Proteins

Raelene Grumont, Wendy L. Washtien, Daniel Caput and Daniel V. Santi

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 977 KB

english, 1986

4

Chemistry and antitumor evaluation of selected classical 2,4-diaminoquinazoline analogs of folic acid

Hynes, J. B., Harmon, S. J., Floyd, G. G., Farrington, M., Hart, L. D., Gale, G. R., Washtien, W. L., Susten, S. S., Freisheim, J. H.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 984 KB

english, 1985

5

Mechanism of action of 5-nitro-2'-deoxyuridine

Washtien, Wendy L., Santi, Daniel V.

Journal:

Journal of Medicinal Chemistry

Year:

1982

Language:

english

File:

PDF, 544 KB

english, 1982

6

Mechanism of inactivation of γ-cystathionase by the acetylenic substrate analog propargylglycine

Washtien, Wendy, Abeles, Robert H.

Journal:

Year:

1977

Language:

english

File:

PDF, 909 KB

english, 1977

7

Synthesis of 5-chloro-5,8-dideaza analogs of folic acid and aminopterin targeted for colon adenocarcinoma

Hynes, J. B., Kumar, A., Tomazic, A., Washtien, W. L.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 752 KB

english, 1987

8

Additions and Corrections-Improved Synthesis and Antitumor Evaluation of 5,8-Dideazaisofolic Acid and Closely Related Analogues

Hynes, J, Yang, Y, McGill, J, Harmon, S, Washtien, W

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 148 KB

english, 1984

9

Improved synthesis and antitumor evaluation of 5,8-dideazaisofolic acid and closely related analogs

Hynes, J. B., Yang, Y. C. S., McGill, J. E., Harmon, S. J., Washtien, W. L.

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 602 KB

english, 1984

10

Novel fluorinated antifolates. Enzyme inhibition and cytotoxicity studies on 2'- and 3'-fluoroaminopterin

Henkin, Jack, Washtien, Wendy L.

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 593 KB

english, 1983

11

Substrate proton exchange catalyzed by γ-cystathionase

Washtien, Wendy, Cooper, Arthur J. L., Abeles, Robert H.

Journal:

Year:

1977

Language:

english

File:

PDF, 485 KB

english, 1977

12

Book Reviews : Gale Jensen, A. A. Liveright, and Wilbur Hallenbeck (Eds.), Adult Edu cation: Outlines of an Emerging Field of University Study. Washington, D. C.: Adult Education Association of the USA. 1964. 334 pp

Washtien, J. L.

Journal:

Adult Education Quarterly

Year:

1972

Language:

english

File:

PDF, 235 KB

english, 1972

13

ChemInform Abstract: Synthesis of 5-Chloro-5,8-dideaza Analogues of Folic Acid and Aminopterin Targeted for Colon Adenocarcinoma.

HYNES, J. B., KUMAR, A., TOMAZIC, A., WASHTIEN, W. L.

Journal:

Year:

1988

File:

PDF, 198 KB

1988

14

Bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania tropica: sequence homology with the corresponding monofunctional proteins.

Grumont, R., Washtien, W. L., Caput, D., Santi, D. V.

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.25 MB

english, 1986

15

ChemInform Abstract: NOVEL FLUORINATED ANTIFOLATES. ENZYME INHIBITION AND CYTOTOXICITY STUDIES ON 2′- AND 3′-FLUOROAMINOPTERIN

HENKIN, J., WASHTIEN, W. L.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 116 KB

1983

16

ChemInform Abstract: IMPROVED SYNTHESIS AND ANTITUMOR EVALUATION OF 5,8-DIDEAZAISOFOLIC ACID AND CLOSELY RELATED ANALOGS

HYNES, J. B., YANG, Y. C. S., MCGILL, J. E., HARMON, S. J., WASHTIEN, W. L.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 215 KB

1984

17

ChemInform Abstract: CHEMISTRY AND ANTITUMOR EVALUATION OF SELECTED CLASSICAL 2,4-DIAMINOQUINAZOLINE ANALOGS OF FOLIC ACID

HYNES, J. B., HARMON, S. J., FLOYD, G. G., FARRINGTON, M., HART, L. D., GALE, G. R., WASHTIEN, W. L., SUSTEN, S. S., FREISHEIM, J. H.

Journal:

Chemischer Informationsdienst

Year:

1985

File:

PDF, 192 KB

1985

18

ChemInform Abstract: IMPROVED SYNTHESIS AND ANTITUMOR EVALUATION OF 5,8-DIDEAZAISOFOLIC ACID AND CLOSELY RELATED ANALOGS

HYNES, J. B., YANG, Y. C. S., MCGILL, J. E., HARMON, S. J., WASHTIEN, W. L.

Journal:

Chemischer Informationsdienst

Year:

1984

File:

PDF, 215 KB

1984

19

ChemInform Abstract: MECHANISM OF ACTION OF 5-NITRO-2′-DEOXYURIDINE

WASHTIEN, W. L., SANTI, D. V.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 92 KB

1983

20

ChemInform Abstract: MECHANISM OF CARBINOLAMINE FORMATION

SAYER, J. M., PINSKY, B., SCHONBRUNN, A., WASHTIEN, W.

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 174 KB

1975

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